Blog 2: BLAST Parkinsons

Accession number: GBYX01449394

The protein I searched for is Poeciliopsis prolifica, also known as Park7, which codes for Parkinson’s disease. Parkinson ’s disease is a neurological condition that affects the central nervous system. This leads slows movement and shaking, especially noticeable in the hands. It measures 1055 base pairs on the chromosome 1.36. I choose Parkinson’s because I can see early stages in people around me, and was always curious about it. It tends to be in older people, and knowing where and how it works can better the future.

The Nucleotide sequence is:

                    1 aaataaattg tctggcgttt ggagcaacta catttaaaat atcagttgga tgaagtcatt

       61 attctgttta cttggaagtg gaaacatact gcagttatct gagagataaa cataatgagc

      121 atctcatatt tattttggag tttccacatt ttcatttgaa atctaagttc taaacagatt

      181 gaacatgcag tttaagaaat gaaagaacaa cagtgtccag atagggggat aaaaggacgc

      241 ggtctggcaa cattcctcct gtcatattcg caccgtgaag cacgcctgac gctgcttgaa

      301 gtttgaagcg tttttgcttc tccaaaagcg aaacattaag ctgatcatgg caggaaagag

      361 agcgttggtg atcctgtcta aaggtgcgga agagatggaa actgtgattc ctgtggacat

      421 catgcgcaga gctgggatta cagtgacggt tgcgggtctc acaggaaaag atccagttga

      481 atgcagcaga agtgttgtca tctgccctga tgccagtctg gaggaagcca gcaaacaggg

      541 gccttatgat gtggtacttc tgcctggagg aatgccagga gccaagaatc tggcagagtc

      601 tcctgctgtg aaggaggtgt taaaggacca agatggcaga aaaggcctga ttgcagccat

      661 ctgtgcaggt ccgaccgctc ttctggctca tggcatcggt tacggcagca cagtcaccac

      721 acatcctggc atgaaggaga agatgatggt tggagatcac tataaatatt cagaagctcg

      781 agtgcagaaa gatgggcatt acatcaccag ccgtgggcca ggaaccagtt ttgagtttgc

      841 cctgacgatc gtagaggaac ttatgggggc tgaggtcgca gctcaagtca aggctcctct

      901 catgatgaaa gactgactgt aatgttctct caccgctctg gtggaactgt gacacctaaa

      961 catctggcta tttctattgc acagcgtttc tgcaaataaa agggaaatca tcactgcata

     1021 attaccacaa atgacttcat agctggcgct cagcc

//

The first 10 Amino Acid name on the sequence is: Phenylalanine, Isoleucine, Stop, Glutamine, Threonine, Alanine, Asparagine, Leucine, Valine, Aspartic Acid. 

 The Amino Acid sequence is:

        1 magkralvil skgaeemetv ipvdimrrag itvtvagltg kdpvecsrsv vicpdaslee

       61 askqgpydvv llpggmpgak nlaespavke vlkdqdgrkg liaaicagpt allahgigyg

      121 stvtthpgmk ekmmvgdhyk ysearvqkdg hyitsrgpgt sfefaltive elmgaevaaq

      181 vkaplmmkd

AUTHORS   Jue,N.K., Foley,R.J., Obergfell,C., Reznick,D.N., O'Neill,R.J. and

            O'Neill,M.J.

  TITLE     Parallel Evolution in Life History Adaptation Evident in the

            Tissue-Specific Poeciliopsis prolifica transcriptome

  JOURNAL   Unpublished