Lab #4: BLAST-B by Tien Pham

     For this assignment I selected a protein, an insulin partial, because I have a chinchilla that loves all kinds of treats, but chinchillas in general have a very sensitive digestive system which makes chinchilla unable to eat that much sugar. This included fruits like apples or pears; they are only able to eat a pinch or two a week because there are too much sugar in them. So I chose to look up the types of insulin in chinchillas to possibility farther understand why they are so sensitive to even the smallest amount of sugar.

     The organism for which the protein insulin partial is located in the Chinchilla chinchilla (short-tailed chinchilla) and the Chinchilla lanigera (long-tailed chinchilla). Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.

Chinchilla chinchilla (short-tailed chinchilla)

Chinchilla lanigera (long-tailed chinchilla)

Accession: AY823468

The amino acid sequence is: 

1 fvnkhlcgsh lvdalylvcg drgffytpma givdqcctsi ctlyqlenyc n

Here is the first 10 translation of amino acids:

Phenylalanine Valine Asparagine Lysine Histidine Leucine Cysteine Glycine Serine Histidine

Reference Citation:

Juan C. Opazo, R. Eduardo Palma, Francisco Melo, Enrique P. Lessa; Adaptive Evolution of the 

Insulin Gene in Caviomorph Rodents, Molecular Biology and Evolution, Volume 22, Issue 5, 

1 May 2005, Pages 1290–1298, https://doi.org/10.1093/molbev/msi117

Nucleotide sequence:

1     tttgtcaaca aacatctgtg cggctcacac ttagtggatg cgctatacct ggtgtgtggg
61   gacagaggct tcttctatac acccatggcc ggcattgtgg atcagtgctg taccagcatc
121 tgcacactct accagctgga gaactactgc aattag